The OB/GYN Virtual Education Series of Ascension Saint Thomas provides an opportunity for those who provide care for women throughout their lifetime to meet their medical and surgical needs. As the body of evidence-based topics evolve, practice gaps such as appropriate diagnosis and treatment of recurrent UTIs become apparent. This enduring material is designed to increase accurate diagnoses and support optimal patient care.
As a result of participating in this activity, learners will:
• Analyze recent data for etiology of urinary tract infections.
• Identify differential and diagnosis of recurrent UTIs.
• Develop strategies for prevention of UTIs.
• Implement appropriate treatment of UTIs.
Sources
• ACOG Practice Bulletin No. 91: Treatment of urinary tract infections in nonpregnant women. Obstet Gynecol. 2016;111(3):785-794.
• Albert X, Huertas I, PereiróIl I, Sanfélix J, Gosalbes V, Perrota C. Antibiotics for preventing recurrent urinary tract infection in non-pregnant women. Cochrane Database Syst Rev. 2004;2004(3):CD001209.
• Anger J, Lee U, Ackerman A, et al. Recurrent uncomplicated urinary tract infections in women: AUA/CUA/SUFU guideline. J Urol. 2019;202(2):282-289.
• Brumfitt W, Hamilton-Miller JM. Efficacy and safety profile of long-term nitrofurantoin in urinary infections: 18 years' experience. J Antimicrob Chemother. 1998;42:363.
• FDA Drug Safety Communications. FDA revises labels of SGLT2 inhibitors for diabetes to include warnings about too much acid in the blood and serious urinary tract infections. December 4, 2015. https://www.fda.gov/drugs/drug-safety-and-availability/fda-revises-labels-sglt2-inhibitors-diabetes-include-warnings-about-too-much-acid-blood-and-serious
• Foxman B. Recurring urinary tract infection: incidence and risk factors. Am J Public Health. 1990;80(3):331.
• Gupta K, Hooton TM, Roberts PL, Stamm WE. Patient-initiated treatment of uncomplicated recurrent urinary tract infections in young women. Ann Intern Med. 2001;135:9.
• Hooton TM, Vecchio M, Iroz A, et al. Effect of increased daily water intake in premenopausal women with recurrent urinary tract infections: a randomized clinical trial. JAMA Intern Med. 2018;178:1509-1515.
• Iravani A, Tice AD, McCarty J, et al. Short-course ciprofloxacin treatment of acute uncomplicated urinary tract infection in women. The minimum effective dose. Arch Intern Med. 1995;155(5):485-494.
• Jepson RG, Williams G, Craig JC. Cranberries for preventing urinary tract infections. Cochrane Database of Systematic Reviews. 2012;Issue 10. Art. No.: CD001321. DOI: 10.1002/14651858.CD001321.pub5.
• Melekos MD, Asbach HW, Gerharz E, et al. Post-intercourse versus daily ciprofloxacin prophylaxis for recurrent urinary tract infections in premenopausal women. J Urol. 1997; 157:935.
• Mysorekar IU, Hutgren SJ. Mechanisms of uropathogenic escherichia coli persistence and eradication from the urinary tract. Proc Natl Acad Sci. 2006 Sep 19;103(38).
• Neugent ML, Hulyalkar NV, Nguyen VH, Zimmern PE, De Nisco NJ. Advances in understanding the human urinary microbiome and its potential role in urinary tract infection. mBio. 2020;11:e00218-20.
• Oplinger M, Andrews CO. Nitrofurantoin contraindication in patients with a creatinine clearance below 60 mL/min: looking for the evidence. Ann Pharmacother. 2013;47:106.
• Rahn DD, Carberry C, Sanses TV, Mamik MM, et al. Vaginal estrogen for genitourinary syndrome of menopause: a systematic review. Obstet Gynecol. 2014; 124(6):1147–1156.
• Schwenger EM, Tejani AM, Loewen PS. Probiotics for preventing urinary tract infections in adults and children. Cochrane Database of Systematic Rev. 2015 Dec 23;2015(12): CD008772.
This activity is designed for OB/GYN physicians, OB/GYN nurse practitioners, OB/GYN physician assistants, primary care physicians, and other healthcare professionals who provide care for patients with obstetric and gynecology needs.